Celebrating the 2017 Nobel Prize for circadian rhythm research: a collection from The Company of Biologists
The 2017 Nobel Prize in Physiology or Medicine was jointly awarded to Jeffrey C. Hall, Michael Rosbash and Michael W. Young for their discoveries of molecular mechanisms controlling the circadian rhythm. It was in 1984 that Jeffrey Hall and Michael Rosbash at Brandeis University in Boston, and Michael Young at the Rockefeller University in New York, discovered the period gene in fruit flies. This gene regulates daily biological rhythms through oscillating expression of the protein PERIOD, which accumulates in cells at night and is degraded through the day.
Since this initial breakthrough, far more has been discovered about biological clocks and the molecular machinery that controls them in fruit flies and other organisms, including humans. The scope of circadian rhythm research across developmental and cellular biology, animal physiology and disease research means that all the journals published by The Company of Biologists have featured articles that have contributed to this field. We are pleased to present a special collection of circadian rhythm research published in Development, Journal of Cell Science, Journal of Experimental Biology, Disease Models & Mechanisms and Biology Open in celebration of this year’s Nobel Prize award. We are especially proud to include an early paper by Jeffrey Hall and Michael Rosbash on the role of circadian pathway genes in the synchronisation of fruit fly larval eclosion, published in Development in 1989.
RESEARCH ARTICLE
Expression of a Drosophila mRNA is under circadian clock control during pupation
Lori J. Lorenz, Jeffrey C. Hall, Michael Rosbash
Development 1989 107: 869-880
CELL SCIENCE AT A GLANCE
Circadian oscillators of Drosophila and mammals
Wangjie Yu, Paul E. Hardin
Journal of Cell Science 2006 119: 4793-4795; doi: 10.1242/jcs.03174
JEB CLASSICS
Circadian window of opportunity: what have we learned from insects?
Jadwiga Giebultowicz
Journal of Experimental Biology 2010 213: 185-186; doi: 10.1242/jeb.034199
COMMENTARY
Mammalian circadian clock and metabolism – the epigenetic link
Marina Maria Bellet, Paolo Sassone-Corsi
Journal of Cell Science 2010 123: 3837-3848; doi: 10.1242/jcs.051649
COMMENTARY
Post-transcriptional control of circadian rhythms
Shihoko Kojima, Danielle L. Shingle, Carla B. Green
Journal of Cell Science 2011 124: 311-320; doi: 10.1242/jcs.065771
RESEARCH ARTICLE
Opsin1-2, Gqα and arrestin levels at Limulus rhabdoms are controlled by diurnal light and a circadian clock
Barbara-Anne Battelle, Karen E. Kempler, Alexander K. Parker, Cristina D. Gaddie
Journal of Experimental Biology 2013 216: 1837-1849; doi: 10.1242/jeb.083519
RESEARCH ARTICLE
The F-box protein ZEITLUPE controls stability and nucleocytoplasmic partitioning of GIGANTEA
Jeongsik Kim, Ruishuang Geng, Richard A. Gallenstein, David E. Somers
Development 2013 140: 4060-4069; doi: 10.1242/dev.096651
REVIEW
Circadian clock-mediated control of stem cell division and differentiation: beyond night and day
Steven A. Brown
Development 2014 141: 3105-3111; doi: 10.1242/dev.104851
RESEARCH ARTICLE
Circadian rhythms affect electroretinogram, compound eye color, striking behavior and locomotion of the praying mantis Hierodula patellifera
Aaron E. Schirmer, Frederick R. Prete, Edgar S. Mantes, Andrew F. Urdiales, Wil Bogue
Journal of Experimental Biology 2014 217: 3853-3861; doi: 10.1242/jeb.102947
RESEARCH ARTICLE
Dynamics of the circadian clock protein PERIOD2 in living cells
Rupert Öllinger, Sandra Korge, Thomas Korte, Barbara Koller, Andreas Herrmann, Achim Kramer
Journal of Cell Science 2014 127: 4322-4328; doi: 10.1242/jcs.156612
RESOURCE ARTICLE
Robust circadian rhythms in organoid cultures from PERIOD2::LUCIFERASE mouse small intestine
Sean R. Moore, Jill Pruszka, Jefferson Vallance, Eitaro Aihara, Toru Matsuura, Marshall H. Montrose, Noah F. Shroyer, Christian I. Hong
Disease Models & Mechanisms 2014 7: 1123-1130; doi: 10.1242/dmm.014399
RESEARCH ARTICLE
The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer’s disease
Ko-Fan Chen, Bernard Possidente, David A. Lomas, Damian C. Crowther
Disease Models & Mechanisms 2014 7: 445-458; doi: 10.1242/dmm.014134
RESEARCH ARTICLE
Transcription factors involved in retinogenesis are co-opted by the circadian clock following photoreceptor differentiation
David Whitmore
Development 2014 141: 2644-2656; doi: 10.1242/dev.104380
RESEARCH ARTICLE
β-adrenergic receptor signaling regulates Ptgs2 by driving circadian gene expression in osteoblasts
Takao Hirai, Kenjiro Tanaka, Akifumi Togari
Journal of Cell Science 2014 127: 3711-3719; doi: 10.1242/jcs.148148
RESEARCH ARTICLE
Do circadian genes and ambient temperature affect substrate-borne signalling during Drosophila courtship?
Izarne Medina, José Casal, Caroline C. G. Fabre
Biology Open 2015 4: 1549-1557; doi: 10.1242/bio.014332
RESEARCH ARTICLE
Functional circadian clock genes are essential for the overwintering diapause of the Northern house mosquito, Culex pipiens
Megan E. Meuti, Mary Stone, Tomoko Ikeno, David L. Denlinger
Journal of Experimental Biology 2015 218: 412-422; doi: 10.1242/jeb.113233
RESEARCH ARTICLE
Heterozygous disruption of activin receptor-like kinase 1 is associated with increased arterial pressure in mice
María González-Núñez, Adela S. Riolobos, Orlando Castellano, Isabel Fuentes-Calvo, María de los Ángeles Sevilla, Bárbara Oujo, Miguel Pericacho, Ignacio Cruz-Gonzalez, Fernando Pérez-Barriocanal, Peter ten Dijke, Jose M. López-Novoa
Disease Models & Mechanisms 2015 8: 1427-1439; doi: 10.1242/dmm.019695
RESEARCH ARTICLE
Phenotypic and functional characterization of Bst+/− mouse retina
Hamidreza Riazifar, Guoli Sun, Xinjian Wang, Alan Rupp, Shruti Vemaraju, Fred N. Ross-Cisneros, Richard A. Lang, Alfredo A. Sadun, Samer Hattar, Min-Xin Guan, Taosheng Huang
Disease Models & Mechanisms 2015 8: 969-976; doi: 10.1242/dmm.018176
RESEARCH ARTICLE
α1B-Adrenergic receptor signaling controls circadian expression of Tnfrsf11b by regulating clock genes in osteoblasts
Takao Hirai, Kenjiro Tanaka, Akifumi Togari
Biology Open 2015 4: 1400-1409; doi: 10.1242/bio.012617
RESEARCH ARTICLE
REV-ERBα influences the stability and nuclear localization of the glucocorticoid receptor
Takashi Okabe, Rohit Chavan, Sara S. Fonseca Costa, Andrea Brenna, Jürgen A. Ripperger, Urs Albrecht
Journal of Cell Science 2016 129: 4143-4154; doi: 10.1242/jcs.190959
REVIEW
Central and peripheral circadian clocks and their role in Alzheimer’s disease
Ruchi Chauhan, Ko-Fan Chen, Brianne A. Kent, Damian C. Crowther
Disease Models & Mechanisms 2017 10: 1187-1199; doi: 10.1242/dmm.030627
RESEARCH ARTICLE
Entraining to the polar day: circadian rhythms in arctic ground squirrels
Cory T. Williams, Brian M. Barnes, Lily Yan, C. Loren Buck
Journal of Experimental Biology 2017 220: 3095-3102; doi: 10.1242/jeb.159889
RESEARCH ARTICLE
Meis1: effects on motor phenotypes and the sensorimotor system in mice
Aaro V. Salminen, Lillian Garrett, Barbara Schormair, Jan Rozman, Florian Giesert, Kristina M. Niedermeier, Lore Becker, Birgit Rathkolb, Ildikó Rácz, Juliane Winkelmann et al.
Disease Models & Mechanisms 2017 10: 981-991; doi: 10.1242/dmm.030080
RESEARCH ARTICLE
REV-ERBα regulates Fgf21 expression in the liver via hepatic nuclear factor 6
Rohit Chavan, Nadia Preitner, Takashi Okabe, Laureen Mansencal Strittmatter, Cheng Xu, Jürgen A. Ripperger, Nelly Pitteloud, Urs Albrecht
Biology Open 2017 6: 1-7; doi: 10.1242/bio.021519