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Novelty, Co-option and Divergence During Gene Network Evolution

Date: 14-17 June 2026

Location: Buxted Park, East Sussex, UK

Organisers: James Hombría and Antónia Monteiro

Recent studies on the evolution of novel traits provide a window of opportunity to understand how existing gene-regulatory networks (GRNs) are redeployed to new developmental contexts during evolution. Several GRNs controlling organ development and physiology have been studied in animal models, but we lack a basic understanding of how these might have evolved. To understand how GRNs change during evolution, at this meeting we will discuss how novelty evolves in existing GRNs, and how such variations are selected to facilitate adaptation.

We hope to bring together researchers working on gene regulation, developmental biology, mathematical modelling and evolution. The invited researchers work on a variety of complex systems and are examining how these systems originated and have evolved over time. By comparing perspectives and experimental approaches to examine the evolution of their specific systems, we hope to draw common threads that may be applicable to most systems, and we aim to highlight these after the meeting in a Review article.